Determination of Levadopa and Benserazide Active Ingredients Used in Parkinson's Treatment by Artificial Neural Networks Method
نویسندگان
چکیده
Bu çalışmada, tablet ilaç numunesinde bulunan levadopa ve benserazid etken maddelerinin aynı anda miktar tayinlerine hiçbir ayırma işlemi uygulanmaksızın ultraviyole görünür bölge spektroskopisi ile tayinleri gerçekleştirilmiş elde edilen veriler yapay sinir ağları (ANN) kemometrik yöntemi değerlendirilmiştir. Çalışmanın sonunda kullanılan karşılaştırmak amacıyla kısmi en küçük kareler (PLS) uygulanmıştır. Yapılan çalışmada maddelerin saf haldeki spektrumları edilmiş takiben sentetik karışımları hazırlanmıştır. karışımlardan ANN değerlendirilmiş yöntem piyasadan alınan numunesine Çalışmada istatistiksel olarak da incelenmiş, yönteminde önemli bir veri grubu olan karekök ortalama hata (RMS) verileri oldukça bulunmuştur. Ayrıca hesaplanan geri kazanım değerleri yüksek, standart sapmaları ise yeterince küçüktür. Uygulanan yardımıyla sonuçlar son derece hızlı, basit güvenilir sonuçlardır.
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ژورنال
عنوان ژورنال: Fen-mühendislik dergisi
سال: 2023
ISSN: ['1302-9304', '2547-958X']
DOI: https://doi.org/10.21205/deufmd.2023257406